主著論文 　(*Corresponding author / †Equally Contributed)

  1. K. Nakajima†,*, T. Ota†, H. Toda, K. Yamaguchi, Y. Goto, and H. Ogi, "Surface Modification of Ultrasonic Cavitation by Surfactants Improves Detection Sensitivity of α-synuclein Amyloid Seeds", ACS Chemical Neuroscience, Vol. 15, 1643-1651 (2024).
  2. K. Nakajima†, K. Yamaguchi†, M. Noji†, C. Aguirre, K. Ikenaka, H. Mochizuki, L. Zhou, H. Ogi, T. Ito, I. Narita, F. Gejyo, H. Naiki, S. Yamamoto*, and Y. Goto*, "Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis", Nature Communications, Vol. 13, 5689 (2022). (関連プレスリリース：人工透析医療の合併症「透析アミロイドーシス」に新リスク因子を発見)
  3. K. Nakajima, T. Tsujimura, K. Doi, and S. Kawano*, "Visualization of optical vortex forces acting on Au nanoparticles transported in nanofluidic channels", ACS Omega, Vol. 7, 2638-2648 (2022).
  4. K. Nakajima†, H. Toda†, K. Yamaguchi, M. So, K. Ikenaka, H. Mochizuki, Y. Goto, and H. Ogi*, "Half-time heat map reveals ultrasonic effects on morphology and kinetics of amyloidogenic aggregation reaction", ACS Chemical Neuroscience, Vol. 12, 3456-3466 (2021).
  5. K. Nakajima, K. Noi, K. Yamaguchi, M. So, K. Ikenaka, H. Mochizuki, H. Ogi, and Y. Goto*, “Optimized sonoreactor for accelerative amyloid-fibril assays through enhancement of primary nucleation and fragmentation”, Ultrasonics Sonochemistry, Vol. 73, 105508 (2021).
  6. K. Nakajima, R. Nakatsuka, T. Tsuji, K. Doi, and S. Kawano*, "Synchronized resistive-pulse analysis with flow visualization for single micro- and nanoscale objects driven by optical vortex in double orifice", Scientific Reports, Vol. 11, 9323 (2021).
  7. K. Nakajima, T. Yamazaki, Y. Kimura, M. So, Y. Goto, and H. Ogi*, "Time-resolved observation of evolution of amyloid-β oligomer with temporary salt crystals", The Journal of Physical Chemistry Letters, Vol. 11, 6176-6184 (2020). (関連プレスリリース：アルツハイマー病の原因物質を「毒性」に変貌させる新しいメカニズムを発見)
  8. K. Nakajima, D. Nishioka, M. Hirao, M. So, Y. Goto, and H. Ogi*, "Drastic acceleration of fibrillation of insulin by transient cavitation bubble", Ultrasonics Sonochemistry, Vol. 36, 206-211 (2017).
  9. K. Nakajima, M. So, K. Takahashi, Y. Tagawa, M. Hirao, Y. Goto, and H. Ogi*, "Optimized ultrasonic irradiation finds out ultrastable Aβ1-40 oligomers", The Journal of Physical Chemistry B, Vol. 121, 2603-2613 (2017).
  10. K. Nakajima, H. Ogi*, K. Adachi, K. Noi, M. Hirao, H. Yagi, and Y. Goto, "Nucleus factory on cavitation bubble for amyloid β fibril", Scientific Reports, Vol. 6, 22015 (2016). (関連プレスリリース：超音波が引き起こす気泡がアルツハイマー病の原因物質生成工場に！)

共著論文 　(*Corresponding author / †Equally Contributed)

  1. S. Yamamoto, K. Yamamoto, Y. Hirao, K. Yamaguchi, K. Nakajima, M. Sato, M. Kawachi, M. Domon, K. Goto, K. Omori, N. Iino, H. Shimada, R. Aoyagi, I. Ei, S. Goto, Y. Goto, F. Gejyo, T. Yamamoto, and I. Narita "Mass spectrometry-based proteomic analysis of proteins adsorbed by hexadecyl-immobilized cellulose bead column for the treatment of dialysis-related amyloidosis", Amyloid, 1-11 (2024).　(関連プレスリリース：透析アミロイドーシスの進展に関連するタンパク質を発見)
  2. Y. Goto, K. Nakajima, S. Yamamoto, and K. Yamaguchi, "Supersaturation, a critical factor underlying proteostasis of amyloid fibril formation", J. Mol. Biol. 168475 (2024).
  3. L. Zhou, T. Hajiri, K. Nakajima, C. Aguirre, K. Ikenaka, H. Mochizuki, K. Yamaguchi, Y. Goto, and H. Ogi*, "Ultra-stiff amyloid-fibril network of α-synuclein formed by surface seeding reaction confirmed by multichannel electrodeless quartz-crystal-microbalance biosensor", ACS Sensors, Vol. 8, 2598-2608 (2023).
  4. C. J. Choong †, C. Aguirre †, K. Kakuda, G. Beck, H. Nakanishi, Y. Kimura, S. Shimma, K. Nabekura, M. Hideshima, J. Doi, K. Yamaguchi, K. Nakajima, T. Wadayama, H. Hayakawa, K. Baba, K. Ogawa T. Takeuchi, S. M. M. Badawy, S. Murayama, S. Nagano, Y. Goto, Y. Miyanoiri, Y. Nagai, H. Mochizuki*, and K. Ikenaka*, "Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson’s disease-related fibril polymorphism", Acta Neuropathologica, Vol. 145, 573-595 (2023) (関連プレスリリース：パーキンソン病の発症の源流を解明)
  5. K. Yamaguchi*, K. Nakajima, and Y. Goto, "Mechanisms of polyphosphate-induced amyloid fibril formation triggered by breakdown of supersaturation", Biophysics and Physicobiology, e200013 (2023).
  6. Y. Goto*, M. Noji, K. Nakajima, and K. Yamaguchi, "Supersaturation-dependent formation of amyloid fibrils", Molecules, Vol. 27, 4588 (2022).
  7. K. Noi, K. Nakajima, K. Yamaguchi, M. So, K. Ikenaka, H. Mochizuki, Y. Goto, and H. Ogi*, "Acceleration of amyloid fibril formation by multichannel sonochemical reactor", Japan Journal of Applied Physics, Vol. 61, SG1002 (2022).
  8. M. Hideshima, Y. Kimura, C. Aguirre, K. Kakuda, T. Takeuchi, C.-J. Choong, K. Nabekura, K. Yamaguchi, K. Nakajima, K. Baba, S. Nagano, Y. Goto, Y. Nagai, H. Mochizuki, and K. Ikenaka*, "Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease", Scientific Reports, Vol. 12, 351 (2022).
  9. Y. Goto*, K. Nakajima, K. Yamaguchi, M. So, K. Ikenaka, H. Mochizuki, and H. Ogi, "Development of HANABI, an ultrasonication-forced amyloid fibril inducer", Neurochemistry International, Vol. 153, 105270 (2022).
  10. R. Nakatsuka, S. Yanai, K. Nakajima, K. Doi, and S. Kawano, "Electrical sensing of Au Nanoparticles manipulated by an optical vortex", The Journal of Physical Chemistry C, Vol. 125, 9507-9515 (2021).
  11. T. Tsuji, R. Nakatsuka, K. Nakajima, K. Doi, and S. Kawano, "Effect of hydrodynamic inter-particle interaction on the orbital motion of dielectric nanoparticles driven by an optical vortex", Nanoscale, Vol. 12, 6673-6690 (2020).



解説記事等

  1. 中島吉太郎, "結晶化という観点からアミロイドーシス予防を考える", 蛋白質科学会アーカイブ, 2024年1月.
  2. 中島吉太郎, 山口圭一, 後藤祐児, "透析アミロイドーシス発症リスクの研究とアミロイドーシス予防戦略", MedChem News, Vol. 33, 193-198 2023年11月.
  3. 中島吉太郎, 山口圭一，荻博次，後藤祐児　"超音波によるアミロイド線維形成反応の誘起とその応用", 高圧力学会誌, Vol. 33, No.2, 2023年.
  4. 中島吉太郎, 山口圭一, 荻博次, 後藤祐児, "超音波を利用した蛋白質アミロイド凝集誘導装置HANABI", 超音波テクノ, 2021年9月.
  5. 山口圭一, 中島吉太郎, 後藤祐児, "ポリリン酸が引き起こすアミロイド線維形成機構", 月間「細胞」, 2021年8月.
  6. 中島吉太郎, 荻博次, "超音波によるタンパク質凝集加速反応の周波数依存性", 超音波テクノ, 2019年9月.
  7. 山田晃大朗, 中島吉太郎, 荻博次, 平尾雅彦, "全反射蛍光顕微鏡とQCMの融合によるアルツハイマー病ペプチドの凝集及び融解ダイナミクスの究明", 超音波テクノ, 2016年11月.
  8. 中島吉太郎, 足立寛太, 荻博次, 平尾雅彦, 後藤祐児, "超音波によるAβペプチドの凝集加速", 超音波テクノ, 2015年7月.



戻る