[輪読会] 最新の研究動向を注視したり、他の研究グループを自分の研究を比較できるようになるためには、学術論文を常日頃から読んでおく必要があります。そこで、研究分野が近しいメンバーを募って、週一回2時間程度の勉強会を開催しています。
これまでに輪読してきた論文や教科書は以下の通りです。


(1) F. Oosawa & M. Kasai, "A theory of linear and helical aggregations of macromolecules" J. Mol. Biol. 4, 10-21 (1962).
(2) T. C. Michaels et al., "Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptides" Nat. Chem. 12, 445-451 (2020).
(3) M. Wilkinson et al., "Disease-relevant β2-microglobulin variants share a common amyloid fold" Nat. Commun. 14, 1190 (2023).
(4) D. S. W. Lee, A. R. Strom & C. P. Brangwynne, "The mechanobiology of nuclear phase separation" APL Bioeng. 6, 021503 (2022).
(5) S. F. Shimobayashi et al., "Nucleation landscape of biomolecular condensates" Nature 599, 503-506 (2021).
(6) 蛋白質分子の機能論(改訂版) 濱口浩三著
(7) A. Okuzumi et al., "Propagative α-synuclein seeds as serum biomarkers for synucleinopathies" Nat. Med. 29, 1448-1455 (2023).
(8) N. Cremades et al., "Direct observation of the interconversion of normal and toxic forms of α-synuclein" Cell 149, 1048-1059 (2012).
(9) T. Ikenoue et al., "Cold denaturation of α-synuclein amyloid fibrils" Angew. Chem. Int. Ed. 53, 7799-7804 (2014).
(10) N. Galvanetto et al., "Extreme dynamics in a biomolecular condensate" Nature 619, 876-883 (2023).
(11) T. Michaels et al., "Amyloid formation as a protein phase transition" Nat. Rev. Phys. 5, 379-397 (2023).
(12) T. Ikenoue et al., "Heat of supersaturation-limited amyloid burst directly monitored by isothermal titration calorimetry" Proc. Natl. Acad. Sci. USA. 111, 6654-6659 (2014).
(13) J. Zhou et al., "Effects of sedimentation, microgravity, hydrodynamic mixing and air-water interface on α-synuclein amyloid formation" Chem. Sci. 11, 3687-3693 (2020).
(14) Y. Yoshimura et al., "Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation" Proc. Natl. Acad. Sci. USA. 109, 14446-14451 (2012).

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